Broncos vs Jaguars Prediction & Betting Tips for NFL Week 2 on 9/20/2026

The Jacksonville Jaguars are set to take on the Denver Broncos in Week 2 of the 2026 NFL Regular Season. This matchup will be held at Empower Field at Mile High, an outdoor stadium in Denver, Colorado. The game is scheduled for Sunday, September 20, 2026, with a 4:05 PM kickoff and will be broadcast on CBS and Paramount+.

Heading into this contest, the Jaguars have momentum on their side, having opened the season with a commanding 34-10 victory over the Cleveland Browns. Under the leadership of Head Coach Liam Coen, the Jaguars' offense, guided by Offensive Coordinator Grant Udinski, was effective in their first outing, amassing 234 passing yards and 126 rushing yards. Defensive Coordinator Anthony Campanile's squad also made a strong start, holding the Browns to just 14 first downs.

On the other hand, the Denver Broncos are looking to bounce back from their Week 1 defeat against the Kansas City Chiefs, where they fell 31-10. Under the guidance of Head Coach Sean Payton, the Broncos struggled offensively, managing only 115 passing yards and 61 rushing yards. The defense, coordinated by Vance Joseph, will need to step up after allowing 220 rushing yards to the Chiefs.

Broncos vs Jaguars At a Glance (Week 2)

• The 2026 Regular Season Week 2 game features the Jacksonville Jaguars against the Denver Broncos.
• Jacksonville Jaguars enter this game with a 1-0 record.
• Denver Broncos are looking for their first win of the season, holding a 0-1 record.
• The game will be played at Empower Field at Mile High in Denver, CO.
• Odds favor the Broncos with a moneyline of -149 and a spread of -2.5.
• The game is scheduled for Sunday, September 20, 2026, at 4:05 PM, and will air on CBS (Paramount+).

Denver Broncos: Mile High Expectations for Week 2

Offensive Performance

The Denver Broncos' offense in the 2026 regular season has been struggling, scoring just 10 points in their season opener. They rank 19th in scoring with an average of 10 points per game, and their offensive yards per game rank 31st in the league at 176 yards.

Passing has been a particular area of concern, with the team ranking 29th in passing yards per game at 115. On the ground, they fare slightly better but still rank 30th with just 61 rushing yards per game.

Defensive Challenges

The Broncos' defense allowed 31 points in their opening game, placing them 13th in the league for opponent scoring. They are ranked 23rd in opponent offensive yards per game, allowing 392 yards.

While their pass defense showed strength by allowing only 172 passing yards, ranking 9th, their rush defense struggled, allowing 220 rushing yards, which ranks them 30th.

Key Players to Watch

Bo Nix, the team's quarterback, threw for 131 yards with one touchdown and one interception against the Chiefs. He will need to improve his performance to lead the offense to success.

On defense, Zach Allen stands out with two sacks in the first game, and Brandon Jones recorded an interception. Their continued performance will be vital in halting the Jaguars' offense.

Injury Report

The Broncos have been hit by injuries, with several players on the injured reserve, including center Michael Deiter and defensive end Matt Henningsen. Their absence could impact both the offensive line and the defensive front.

Jonathon Cooper is also unavailable due to off-the-field issues, further testing the depth of the Broncos' roster.

Upcoming Games

Following their game against the Jaguars, the Broncos will face the Los Angeles Rams at home. They will then hit the road to play the San Francisco 49ers and Los Angeles Chargers.

These games will be critical as the Broncos look to bounce back from their opening loss and establish momentum in the season.

Betting Trends

• The Broncos have won 86.7% of their last 15 regular-season games.
• They have a 90% win rate in their last 10 regular-season games as favorites.
• At home, they have won 87.5% of their last 8 regular-season games.
• They have a 66.7% over/under record after a win in their last 6 regular-season games.
• The team has covered the spread in 75% of their last 4 home games.

The Jacksonville Jaguars Roar into Denver: A Game Preview

Quarterback Spotlight

Trevor Lawrence stands out as a key player for the Jaguars, already showing his passing prowess in the season opener against the Browns. He completed 18 passes for 245 yards and threw four touchdowns with no interceptions. His performance places him at the top of league rankings for passing touchdowns and fantasy points.

Lawrence's ability to maintain a clean sheet with zero interceptions will be crucial as they face the Denver Broncos. His connection with wide receivers and tight ends like Parker Washington and Brenton Strange will be vital in maintaining offensive momentum.

Running Backs on the Move

Bhayshul Tuten leads the Jaguars' rushing attack, gaining 66 yards in their previous game. His dual-threat capability was evident with a reception adding 22 yards to his tally. Tuten's performance in both rushing and receiving adds a versatile dimension to the Jaguars' offense.

Supporting him are Ameer Abdullah and Chris Rodriguez Jr., who combined for 55 rushing yards. With a balanced ground attack, the Jaguars aim to diversify their offensive strategies against Denver.

Defensive Powerhouses

The Jaguars' defense is a formidable force, especially highlighted by their Week 1 performance against Cleveland. Josh Hines-Allen and Travon Walker contributed significantly with 1.5 sacks each. This defensive line's ability to apply pressure will be key against the Broncos' offense.

Ventrell Miller also made an impact with six solo tackles and one sack. The unit's overall strength lies in their ability to limit the opponent's rushing yards, which they held to just 87 yards last week.

Key Matchups to Watch

The Jaguars' secondary, led by Eric Murray and Antonio Johnson, will be tested against the Broncos' passing game. Their ability to prevent deep plays will be crucial. On offense, Parker Washington, with his 83 receiving yards and a touchdown, is a player to watch as he looks to exploit the Broncos' defensive gaps.

The Jaguars' depth in wide receivers and tight ends, including Jakobi Meyers and Brenton Strange, will aim to create mismatches. Their diverse passing game could prove challenging for Denver's secondary.

Team Betting Trends

• Jaguars have a 9-0 record in their last 9 regular-season games.
• Against the spread (ATS), they are 9-0 in their last 9 regular-season games.
• After a win, they have an 8-0 record in their last 8 regular-season games.
• As underdogs, they have a 3-0 record in their last 3 regular-season games.
• The over/under is 5-1 in their last 6 regular-season games.

Broncos vs Jaguars Prediction: Over 45.5

The Jacksonville Jaguars come into this game with a potent offense, having scored 34 points in their opening game of the season. Their strong offensive showing places them in the top 10 for both passing and rushing yards. With an aggressive play-calling strategy under Coach Liam Coen, they are likely to put up significant points against the Broncos.

On the other hand, the Denver Broncos struggled offensively in their first game, scoring just 10 points, but playing at home can often provide a boost. The Broncos have a history of better offensive output in home games, and with head coach Sean Payton at the helm, adjustments are expected. Their defense gave up 31 points previously, suggesting vulnerabilities that the Jaguars could exploit.

Historically, matchups between these teams at Empower Field have seen high-scoring outcomes, including a 34-20 result in favor of the Jaguars last season. The Broncos' defense ranking 23rd in opponent offensive yards adds to the probability of a high-scoring game. The Broncos' top betting trends also support an over, with a 57.1% rate of games going over in recent seasons.

Given the offensive capabilities of the Jaguars and the Broncos' potential for improvement at home, the over on 45.5 points seems a promising pick. A projected final score could see the Jaguars winning 28-21, ensuring the total surpasses the set line.

• Broncos vs Jaguars Prediction: Over 45.5
• Broncos vs Jaguars Score: Jaguars 28 - Broncos 21

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