The Ohio State Buckeyes, ranked number two in both the AP and Coaches Polls, travel to Los Angeles for a pivotal Big Ten matchup against the USC Trojans. With a 6-1 record and a perfect 4-0 in conference play, Ohio State's season is on track for a strong finish. They are coming off a victory against the Indiana Hoosiers, winning 19-15. USC, ranked 25th in the Coaches Poll, looks to defend their home field at the Los Angeles Memorial Coliseum. The Trojans hold a 6-2 record, including a 4-1 record at home, and are aiming to bounce back from a recent 24-7 defeat against the Wisconsin Badgers. A win against Ohio State could boost their standing in the Big Ten. The game is set for a prime-time slot on NBC, kicking off at 7:30 PM. Ohio State enters the game favored with a spread of -7, while the Trojans look to leverage their home advantage to challenge the Buckeyes. Fans can anticipate a competitive encounter as both teams seek to strengthen their positions within the conference.

USC vs Ohio State At a Glance (Week 9)

  • Game Venue: Los Angeles Memorial Coliseum, Los Angeles, CA
  • Date & Time: Saturday, October 31, 2026, 7:30 PM
  • Ohio State Record: 6-1 this season
  • USC Record: 6-2 this season
  • Broadcast: NBC
  • Betting Odds: Ohio State favored with a moneyline of -255

The USC Trojans Eye Redemption at Home

Offensive Insights

The USC Trojans have demonstrated a robust passing offense this season, ranking 3rd nationally with 2,429 passing yards. Quarterback Jayden Maiava leads the charge with 2,303 yards and 19 touchdowns, showcasing his ability to drive the ball downfield.

Despite a high-ranking passing game, the rushing attack has not been as effective, ranking 80th with 1,064 yards. Running back King Miller remains a key player, leading the team with 603 rushing yards and 4 touchdowns.

Defensive Challenges

USC's defense has had its struggles, ranking 113th in points against with 200 allowed this season. However, their ability to pressure the quarterback is noteworthy, with 17 sacks placing them 12th nationally.

The secondary has been opportunistic, ranking 4th with 3 interceptions. This defensive unit will need to tighten up and maintain consistency to support the Trojans' winning aspirations.

Recent Performances

In their last outing, the Trojans fell to Wisconsin 24-7, a game marked by a significant struggle in the rushing department, managing -17 yards. However, they showed resilience in earlier games, securing a 31-23 win against Penn State and a 25-21 victory over Washington.

The Trojans' ability to bounce back after a loss has been evident, with a perfect 7-0 record in such situations since 2024. This resilience will be crucial as they prepare for their next challenge at home.

Injury Impact

The Trojans face injury concerns with several players listed as questionable, including linebacker Roman Marchetti and wide receiver Terrell Anderson. Corey Simms and Kilian O'Connor are confirmed out, which could impact the team's depth and performance.

Mark Bowman's status is also uncertain, potentially affecting the tight end rotation. The coaching staff will need to adjust and ensure the next men up are ready to step into key roles.

Team Betting Trends

  • SU - As Favorite: 16-2 (88.9%)
  • SU - After Loss: 7-0 (100.0%)
  • SU - Home Games: 11-1 (91.7%)
  • SU - All Games: 17-6 (73.9%)
  • O/U - Home Games: 20-10 (66.7%)
  • O/U - As Underdog: 9-5 (64.3%)

The Ohio State Buckeyes Prepare for USC Showdown: A Preview

Quarterback Analysis

The USC Trojans will be led by their starting quarterback, whose performance will be crucial in this game. With the Ohio State defense ranking 5th in interceptions this season, any mistakes by the Trojans' quarterback could be costly. Maintaining composure under pressure will be key to avoiding turnovers.

Expect the Trojans' passing game to be tested, as Ohio State's defense is also ranked 19th in sacks. The ability of the quarterback to make quick decisions and elude the Buckeyes' pass rush will be a significant factor in USC's offensive success.

Running Game Dynamics

USC's running game will need to make an impact to balance their offensive attack. With Ohio State's defense being strong against the pass, establishing the ground game could relieve pressure on the quarterback. Look for the Trojans to utilize their running backs to exploit any potential weaknesses in Ohio State's rushing defense.

Ohio State's defense is not among the top in rushing defense, ranked 78th in the nation. USC's strategy might involve testing the run defense early to set the tone and control the game tempo.

Receiving Corps and Key Matchups

USC's wide receivers will face a tough challenge against Ohio State's secondary, which has been effective this season. Precision in route running and securing catches will be crucial for the Trojans' success through the air.

The Trojans will need their receivers to create separation and execute on big plays. Watch for potential mismatches that USC can exploit, particularly against any injuries in the Buckeyes' secondary.

Team Betting Trends

  • SU - Home Games: USC's performance at home has been strong, and this game will test their home advantage.
  • SU - As Underdog: The Trojans have shown resilience in games where they are not the favorites.
  • ATS - All Games: USC's ability to cover the spread has been notable, especially in high-stakes games.
  • O/U - Totals ≥ 50: Games involving USC often see high scoring, and this contest could follow that trend.

USC vs Ohio State Week 9 Prediction: Over 50.5

Ohio State enters this game ranked 2nd in the AP Poll, showcasing an impressive offensive lineup. With 275 points scored this season, they rank 13th in points for, emphasizing their offensive capabilities. Ohio State's strong passing game, ranked 10th, contributes significantly to their scoring potential, making the 'Over' an attractive option.

USC's offensive statistics also suggest a high-scoring game, as they have accumulated 262 points, ranking them 19th in points for. With a passing game ranked 3rd, USC's ability to put up points should not be underestimated. The combination of both teams' offensive strengths suggests that exceeding 50.5 points is within reach.

While Ohio State's defense is solid, ranking 44th in points against, their recent games have shown some vulnerability. Their last game against Indiana ended with a 19–15 victory, suggesting room for opponents to score. USC's ability to perform well at home, with a 4-1 record, further supports the likelihood of a competitive, high-scoring game.

Taking into account both teams' offensive prowess and recent performances, a projected final score of Ohio State 31 - USC 24 seems plausible. This outcome would comfortably exceed the total of 50.5 points, making the 'Over' the optimal pick for this matchup.

  • USC vs Ohio State Prediction: Over 50.5
  • USC vs Ohio State Score: Ohio State 31 - USC 24

Disclaimer: Knup Predictions are for entertainment and informational purposes only. Must be 21+ where applicable. Please gamble responsibly. If you or someone you know has a gambling problem, call 1-800-GAMBLER.

Stay Ahead

Get more picks and sports insights in your inbox

Subscribe to the Knup newsletter for weekly CFB previews, sports business notes, and ecosystem updates.