Oklahoma State vs Colorado Prediction & Betting Tips for Week 8 on 10/24/2026

The Colorado Buffaloes head into Week 8 of the 2026 regular season with a 2-4 record, seeking their first conference win of the season. They face a formidable challenge on the road against the Oklahoma State Cowboys at Boone Pickens Stadium in Stillwater, OK. The Buffaloes have struggled in conference play, currently sitting at 0-3, and will look to turn their fortunes around in this night game broadcasted on FS1.

Oklahoma State has enjoyed a strong start to their season, boasting a 4-2 overall record and an impressive 3-0 mark at home. They are 2-1 in Big 12 conference games, reflecting their competitive edge within the league. The Cowboys are coming off a narrow defeat to the Houston Cougars and will aim to bounce back on their home field.

Heading into this matchup, the odds are stacked against the Buffaloes, with a moneyline of +426 compared to the Cowboys’ -582. The spread suggests a 13.5-point advantage for Oklahoma State, indicating the expectations of their strong performance. As both teams prepare for this clash, the Cowboys will look to maintain their dominant home form, while the Buffaloes aim for an upset to spark their season.

Oklahoma State vs Colorado At a Glance (Week 8)

• Game Location: Boone Pickens Stadium in Stillwater, OK
• Game Time: Saturday, October 24, 2026 at 7:00 PM
• TV Channel: FS1
• Colorado Record: 2-4 overall, 0-3 in conference
• Oklahoma State Record: 4-2 overall, 2-1 in conference
• Game Odds: Oklahoma State favored by 13.5 points

Oklahoma State Cowboys Aim to Defend Their Turf Against the Buffaloes

Offensive Strategy and Performance

The Oklahoma State Cowboys have showcased a significant improvement in their offensive game this season. With 1,977 passing yards ranking them 12th nationally, their aerial attack is a key component. The rushing game has also contributed with 1,142 yards, positioning them 49th, highlighting a balanced offensive strategy.

Quarterback Drew Mestemaker is at the helm, with 1,940 passing yards and 16 touchdowns to his name. His leadership on the field has been crucial in orchestrating the offense's success. The Cowboys’ ability to secure 157 first downs ranks them 16th, underscoring their efficiency in moving the chains.

Defensive Insights

Oklahoma State's defense has been resilient, allowing 142 points this season and placing them 80th nationally. Their defense excels in creating turnovers, with 5 interceptions ranking 6th and 2 fumbles recovered ranking 9th. The Cowboys' 11 sacks contribute to their 14th national rank, emphasizing their ability to apply pressure on opposing quarterbacks.

The defense's turnover creation has been pivotal in shifting game momentum and providing the offense with favorable field positions. Maintaining this defensive pressure will be essential in their upcoming contest against the Colorado Buffaloes.

Key Players to Watch

Running back Caleb Hawkins is a standout performer with 592 rushing yards and 20 receptions. His dual-threat capability makes him a versatile asset in both the running and passing game. Wide receiver Wyatt Young leads the receiving corps with 561 yards and 5 touchdowns, showcasing his role as a primary target for Mestemaker.

Justin Bowick also adds depth to the receiving unit with 469 yards and 6 touchdowns. The chemistry between these receivers and Mestemaker will be vital for the Cowboys' offensive success.

Home Field Advantage

The Cowboys have been formidable at Boone Pickens Stadium, boasting a perfect 5-0 record against the spread in their last five home games. Their ability to capitalize on the home field advantage is reflected in their consistent performances. This matchup against the Buffaloes will be another test of their home dominance.

Injury Report

Oklahoma State faces some challenges with Landon Dean and Mose Phillips III listed as questionable. Additionally, Jacob Sexton's season-ending leg injury is a significant blow to their offensive line depth. The status of these players could impact the Cowboys' game plan and rotation.

Betting Trends

• ATS - As Underdog: Last 7 Games → 7-0 (100.0%)
• SU - As Favorite: Last 30 Games → 23-7 (76.7%)
• ATS - All Games: Last 10 Games → 9-1 (90.0%)
• ATS - Home Games: Last 5 Games → 5-0 (100.0%)
• ATS - Totals ≥ 50: Last 5 Games → 5-0 (100.0%)

As the Cowboys prepare for their matchup with the Buffaloes, their recent form and betting trends suggest a promising outlook. Their strong performance at home and ability to cover spreads highlight their potential for another victorious outing.

Colorado Buffaloes Gear Up for an Exciting Showdown

Offensive Overview

The Colorado Buffaloes have had a challenging start to their season, sitting at 1-4 in their last five games. Offensively, they rank 91st in points scored, with a total of 117 so far this season. Their passing game ranks 61st with 1,523 yards, showcasing some potential in the air.

Despite their struggles, the rushing attack has room for improvement, currently positioned at 97th with 851 rushing yards. The Buffaloes have managed to secure a respectable 44th rank in first downs, indicating their ability to move the chains when it counts.

Defensive Challenges

On the defensive side, Colorado has allowed 154 points against them, placing them 90th in the rankings. Their defense has shown strength in pass rush, achieving 15 sacks and ranking 10th overall. Additionally, the Buffaloes have managed to secure four interceptions, ranking them 5th in this category.

Fumble recoveries have also been a bright spot for the Buffaloes' defense, with three recoveries ranking them 8th. The defense will need to step up to contain their upcoming opponents and improve their current standing.

Key Players to Watch

Quarterback Isaac Wilson has been a focal point for the Buffaloes, with 699 passing yards and four touchdowns over four games. His counterpart, Julian Lewis, has thrown for 733 yards and six touchdowns, offering depth in the quarterback position.

In the backfield, JaQuail Smith and Micah Welch lead the rushing efforts with 259 and 220 yards, respectively. Joseph Williams has been a standout receiver, recording 508 yards and five touchdowns over six games.

Injury Concerns

The Buffaloes are dealing with several injuries, including Kam Perry and Sam Gadie, both listed as questionable. Their availability could impact the team's depth and performance on both sides of the ball.

Other key players, such as Danny Scudero and Zach Atkins, are also uncertain to play, which could affect their passing and receiving options in the upcoming games.

Betting Trends

• As a favorite, the Buffaloes have a strong 17-3 record in their last 20 games.
• Following a win, the team is 2-0-1 in their last three games.
• In home games, they have gone 13-7-1 against the Over/Under line in their last 21 contests.
• They are 7-3 against the spread as a favorite in their last 10 games.
• After a loss, the Buffaloes have a 14-10 record against the spread in their last 24 games.

Oklahoma State vs Colorado Week 8 Prediction: Oklahoma State -13.5

Oklahoma State enters this matchup with a strong home record of 3-0 and a 4-2 overall record. Their offensive capabilities rank them 29th in the nation for points scored, and their defense ranks 80th in points allowed. Playing at Boone Pickens Stadium, they have shown a consistent ability to cover spreads, especially as favorites.

The Cowboys have been exceptional against the spread (ATS) in recent games, boasting a 9-1 record in their last ten outings. Particularly at home, they are 5-0 ATS in their previous five games. These trends support the confidence in Oklahoma State's ability to cover the -13.5 spread against a struggling Colorado team.

Colorado, with a 2-4 record and 0-3 in conference play, faces challenges on both ends. Their road performance has been lackluster at 1-2, and their defense has been vulnerable, ranking 90th in points against. This puts them at a significant disadvantage against Oklahoma State's potent offense.

Given Oklahoma State's home field advantage and recent performance trends, they are well-positioned to cover the spread of -13.5. I project a final score of Oklahoma State 38 - Colorado 17, which aligns with the Cowboys' recent scoring patterns and defensive strength.

• Oklahoma State vs Colorado Prediction: Oklahoma State -13.5
• Oklahoma State vs Colorado Score: Oklahoma State 38 - Colorado 17

Disclaimer: Knup Predictions are for entertainment and informational purposes only. Must be 21+ where applicable. Please gamble responsibly. If you or someone you know has a gambling problem, call 1-800-GAMBLER.